
Between February 28 and March 4, 2026, the Middle East descended into full-scale regional war following a coordinated U.S.-Israeli attack on Iran that killed Supreme Leader Ali Khamenei. This timeline tracks the rapid escalation from the initial strikes through retaliatory attacks, political chaos over succession, and expanding military operations across multiple countries.
15 events · 3 days · 24 source articles
The United States and Israel launched large-scale coordinated military strikes against Iran in the early hours of Saturday, February 28. President Donald Trump announced the operation, code-named 'Epic Fury,' targeting Iranian military infrastructure, nuclear facilities, and leadership positions. The attacks marked the beginning of what would become a regional war.
Iranian Supreme Leader Ayatollah Ali Khamenei, who had ruled Iran since 1989, was killed when his office in Tehran was struck during the U.S.-Israeli operation. President Trump initially announced the death, which was later confirmed by Iranian state media. The assassination represented a devastating blow to the Iranian regime and eliminated the country's most powerful figure after 37 years in power.
Iranian state television officially confirmed the death of Supreme Leader Ali Khamenei on Sunday, March 1, describing it as 'martyrdom' in a joint American-Israeli attack. The government declared 40 days of national mourning and seven public holidays. Mixed reactions erupted across Iran, with some citizens celebrating in the streets while others mourned.
The Islamic Revolutionary Guard Corps announced it had launched the sixth wave of retaliatory attacks, targeting 27 U.S. military bases across the Middle East. Iranian forces also struck targets in Israel and Arab nations hosting American bases. The Port of Duqm in Oman was hit by Iranian drones, injuring workers. The conflict rapidly expanded into a regional war affecting multiple countries.
Reports confirmed that Mojtaba Khamenei, the son of Ali Khamenei who was widely considered the likely successor, was also eliminated in the attacks. This development created additional uncertainty about Iran's political future and succession process. President Trump later claimed that 48 Iranian leaders had been eliminated in the operation.
Major airports in Dubai, Doha, and Abu Dhabi were closed or severely restricted due to the conflict, leaving aircraft and crews stranded worldwide. The closure of these key transit hubs disrupted global aviation schedules, affecting passengers on routes completely unrelated to the Middle East. A significant portion of the region's airspace remained closed.
Global reactions varied widely. EU Commission President Ursula von der Leyen saw potential for a new beginning while warning of instability risks. Turkish President Erdogan expressed sadness over Khamenei's death. The international community remained divided on whether the assassination would bring positive change or further destabilization to the region.
Tehran established an interim leadership council as required by the Iranian constitution, with Ayatollah Alireza Arafi temporarily assuming the Supreme Leader's duties. The council, composed of the president, head of judiciary, and a member of the Guardian Council, faced the challenge of selecting a permanent successor amid ongoing military operations. Iran rejected any possibility of negotiations with Washington.
Oil prices were expected to surge 9-10% from Friday's $67 per barrel closing price after the Strait of Hormuz, through which one-fifth of the world's oil and gas passes, was effectively blocked. Eastern European countries with high energy import dependence faced particular vulnerability. The conflict prompted discussions in Germany about reopening the Nord Stream pipeline and reconsidering Europe's relationship with Russian gas.
On the fourth day of war, Israeli forces entered southern Lebanon with ground troops. The Lebanese army withdrew from at least seven positions along the border as Israeli forces advanced. This expansion of the conflict opened a new front beyond the direct U.S.-Israeli operations inside Iran.
Iranian forces attacked the U.S. Embassy in Riyadh, Saudi Arabia, along with other American bases in the region. The strike on Saudi territory demonstrated Iran's willingness to target U.S. interests throughout the Gulf, potentially drawing more Arab states directly into the conflict. The death toll in Iran had reached 787 according to Iranian Red Crescent reports.
Coalition forces attacked the building in Qom that housed the Assembly of Experts, the body responsible for selecting Iran's new Supreme Leader. The strike on this institution severely disrupted the succession process and demonstrated the intent to prevent a smooth transition of power. The building was severely damaged in the bombardment.
President Trump provided multiple, sometimes contradictory justifications for the military intervention within 72 hours, including regime change, stopping nuclear and ballistic missile programs, and helping Iranian protesters. When asked if Israel had forced America's hand, Trump suggested it might have been the reverse. The actual intelligence basis for claims of an imminent Iranian threat remained unclear.
A senior Pentagon official formally attributed the killing of Supreme Leader Khamenei to Israel, clarifying the chain of command in the operation. Meanwhile, an Iranian drone struck the U.S. Consulate in Dubai on Tuesday evening, demonstrating Iran's continued capability to strike American diplomatic facilities. The conflict entered its fifth day with no signs of de-escalation.
As the war entered its fifth day, Israel issued a stark warning that it would assassinate any successor to Ali Khamenei who was chosen to lead Iran. This threat effectively aimed to prevent any legitimate succession process and maintain maximum pressure on the Iranian regime. International evacuation flights began operating, with Hungary launching repatriation missions for citizens stranded in the region.