The protein carriers of hundreds of lipids have been identified

Nature News · Feb 25, 2026 · Collected from RSS

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RESEARCH BRIEFINGS 25 February 2026 Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to measure which lipids are captured by the more than 130 known human lipid-transfer proteins, providing a valuable resource that reveals some principles of how these transporters work. This is a summary of: Titeca, K. et al. Systematic analyses of lipid mobilization by human lipid transfer proteins. Nature https://doi.org/10.1038/s41586-025-10040-y (2026). Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 € / 30 days cancel any time Subscribe to this journal Receive 51 print issues and online access 185,98 € per year only 3,65 € per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Additional access options: Log in Learn about institutional subscriptions Read our FAQs Contact customer support doi: https://doi.org/10.1038/d41586-026-00570-4‘Expert opinion’ and the figure are published under a CC BY 4.0 licence. Referencesvan Meer, G., Voelker, D. R. & Feigenson, G. W. Nature Rev. Mol. Cell Biol. 9, 112–124 (2008).Article PubMed Google Scholar Iglesias-Artola, J. M. et al. Nature 646, 474–482 (2025).Article PubMed Google Scholar Reinisch, K. M. & Prinz, W. A. J. Cell Biol. 220, e202012058 (2021).Article PubMed Google Scholar Maeda, K. et al. Nature 501, 257–261 (2013).Article PubMed Google Scholar Download references Related Articles Read the paper: Systematic analyses of lipid mobilization by human lipid transfer proteins A protein tunnel that shuttles lipids around the cell Visualizing lipid transport in cells Subjects Latest on: Cell biology Metabolism Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate Article 25 FEB 26 CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly Article 25 FEB 26 CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis Article 25 FEB 26 CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly Article 25 FEB 26 CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis Article 25 FEB 26 Are obesity drugs causing a severe complication? What the science says News Explainer 20 FEB 26