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Nature News
Published 12 days ago

Robust partitioning of cell contents by physical instabilities and biological clocks

Nature News · Feb 11, 2026 · Collected from RSS

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RESEARCH BRIEFINGS 11 February 2026 In early embryos, the first cell divisions must be extremely rapid and precisely controlled to ensure successful development. This balance is found to arise from a tight coupling between the clock that drives the cell-division cycle and a physical instability in the cell skeleton. This coupling robustly partitions cell contents and drives development. This is a summary of: Rinaldin, M. et al. Robust cytoplasmic partitioning by solving a cytoskeletal instability. Nature https://doi.org/10.1038/s41586-025-10023-z (2026). Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 € / 30 days cancel any time Subscribe to this journal Receive 51 print issues and online access 185,98 € per year only 3,65 € per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Additional access options: Log in Learn about institutional subscriptions Read our FAQs Contact customer support doi: https://doi.org/10.1038/d41586-026-00021-0‘Expert opinion’ and the figure are published under a CC BY 4.0 licence. ReferencesNiklas, K. J. & Kutschera, U. Biol. Theory 17, 181–185 (2022).Article Google Scholar Cheng, X. & Ferrell, J. E. Jr Science 366, 631–637 (2019).Article PubMed Google Scholar Nguyen, P. A. et al. Science 346, 244–247 (2014).Article PubMed Google Scholar Donoughe, S., Hoffmann, J., Nakamura, T., Rycroft, C. H. & Extavour, C. G. Nature Commun. 13, 3889 (2022).Article PubMed Google Scholar Download references Related Articles Read the paper: Robust cytoplasmic partitioning by solving a cytoskeletal instability A phase transition for chromosome transmission when cells divide A hybrid control model for the eukaryotic cell cycle Subjects Latest on: Developmental biology Cell biology Coffee linked to slower brain ageing in study of 130,000 people News 09 FEB 26 Evolutionary insights into a skin fold News & Views 04 FEB 26 Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness Article 04 FEB 26 PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling Article 04 FEB 26 Single-molecule dynamics of the TRiC chaperonin system in vivo Article 04 FEB 26 A history of hocus pocus: witchcraft down the ages News & Views 03 FEB 26


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