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节后门诊爆满 , 这种  神器  火了 ! 有人用后呕吐 、 厌食 , 医生紧急提醒
health.ycwb.com
Published about 8 hours ago

节后门诊爆满 , 这种 神器 火了 ! 有人用后呕吐 、 厌食 , 医生紧急提醒

health.ycwb.com · Feb 26, 2026 · Collected from GDELT

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Published: 20260226T084500Z

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“每逢佳节胖三斤”。春节刚过,初八上班第一天,湖北省中医院肥胖专科的号就挂满了,武汉市第三医院内分泌科的肥胖亚专科门诊。同样迎来一波就诊高峰,其中不乏专程来咨询“减肥针”的患者。目前,我国上市的减肥针主要包括司美格鲁肽、替尔泊肽、利拉鲁肽、贝那鲁肽和玛仕度肽。打了就能瘦吗?所有人都适合打吗?有没有副作用?停药后会不会反弹?记者走进医院肥胖专科门诊,从一线临床视角探寻答案。减肥针本质是降糖药男大学生3个月瘦30斤减肥针在医学上属于新型降糖药,即肠促胰素类药物,包括胰高糖素样肽-1(GLP-1)受体激动剂(司美格鲁肽等),以及GLP-1和胰高糖素(GCG)(玛仕度肽)、葡萄糖依赖性促胰岛素多肽(GIP)(替尔泊肽)多重受体激动剂。它们之所以能减肥,可以理解为其让胃排空变慢,不容易饿,并向大脑报告“饱了”的信号,吃得少后,血糖波动变缓,体重随之降低。作为最新上市的国产双靶点药物,玛仕度肽是全球首创的GLP-1/GCG双受体激动剂。在GLP-1降低食欲的同时,GCG靶点还能提高代谢,让白色脂肪棕色化、产生热量,对肝脏脂肪的分解和降低有较好作用。“肥胖是一种病。在临床应用中,玛仕度肽适合肥胖合并糖尿病、血糖控制不佳、脂肪肝的患者。”湖北省中医院肥胖专科主任肖明中表示,2025年下半年以来,肥胖专科门诊也开始将玛仕度肽等减肥针和中医疗法相结合,实践证实减重效果有显著提升。去年12月初,一名207斤的男大学生因体重超标走进肥胖专科。诊断显示,他肥胖合并脂肪肝、肝功能不全、胰岛素抵抗、高尿酸血症和高脂血症,前期多种方法治疗效果不佳。趁着寒假,他在省中医院肥胖专科接受系统中西医结合治疗,通过玛仕度肽、中药内服和中医禁食疗法、规范健康管理,3个月瘦了30斤。“随着体重下降,肝功能等各项指标也逐渐恢复正常。”肖明中说,男孩复诊时判若两人,原来乏力、精神萎靡、失眠,如今精神状态焕然一新,人也自信了,主动说要开始运动锻炼。不是所有人都适合打减肥针有人打针后呕吐、闭经、厌食然而,减肥针并非人人适用。武汉市第三医院内分泌科主治医师李广利介绍,其使用情况主要分为两种:一是BMI(身体质量指数)≥28kg/m²的肥胖患者,二是BMI值在24~28之间,且合并至少一项代谢异常,如糖尿病、高血压、脂肪肝等。“超出这个范围的减脂人群,自行使用针剂可能产生严重副作用。”李广利曾接诊过一名20岁的女孩,身高160厘米,体重110斤左右,BMI值正常,也无任何代谢异常。但她体型焦虑严重,通过非正规渠道自行购买替尔泊肽注射。一个月后体重减少10斤,但她仍不满足,继续用药。3个月后月经稀少,半年后彻底闭经,同时出现厌食症倾向。就诊时,女孩已严重营养不良,身体虚弱,情绪焦虑,需要心理科、营养科联合干预。肖明中则从中医临床角度提出了使用标准:“同样是打减肥针,‘实胖’和‘虚胖’人群的效果大不相同。”实胖就是实实在在吃得多、食欲旺盛、人很壮实,这类人群打针效果较为明显,副作用也表现小。而虚胖人群是“喝凉水都胖”的类型,日常表现为乏力、易疲劳、臃肿、怕冷,“他们的打针效果,在临床上就没那么明显,恶心、便秘、腹胀等副作用也更容易出现”。那么,正规医院的减重门诊是如何规范使用减肥针的?肖明中介绍,初诊时医生会全面评估患者是否适合用药:详细询问病史,检查血脂、血糖、尿酸、肝功能、肾功能、甲状腺功能、胰岛功能等指标,必要时加做甲状腺彩超。孕期、哺乳期女性,以及有甲状腺髓样癌个人或家族史、胰腺疾病、严重胃肠道疾病、严重肝肾功能不全等人群,均禁止使用。对于市面上流行的五类减肥针,医生会根据合并症、耐受性、经济承受力、依从性等维度为患者选择。“比如患者有重度脂肪肝,我们会优先考虑玛仕度肽;如果已有糖尿病,且有心脑血管病的高危因素,司美格鲁肽在综合治疗方面的优势较为明显。”李广利说。减肥针停针后复胖率达80%健康生活方式才是减重根本无论是单靶点还是双靶点,进口还是国产,两位专家反复强调一个核心观点:药物减重永远无法替代健康的生活方式。“减肥针能协助患者克服遗传和生物学层面的饥饿感、代谢阻力,但不能让人长期、健康地‘躺瘦’。”肖明中直言,单纯打针停药后,体重反弹率可以达到80%以上。他打了个比喻,患有肥胖症的人像出故障的车,医生就是4S店的修理工,把车修好了,但车开回去之后,如果驾驶习惯不改,过几天车又得送回4S店。人的体重一样。那什么样的人才能成功维持体重?“通过各种诊疗方法回到正常体重,身体紊乱得到修复,最终主动改变不良生活方式的人。”李广利说,药物早期的抑制食欲作用会让人瘦下来,但如果后续不主动控制,食欲也会慢慢恢复,“能维持住的人,都是在主观意愿上下了功夫的。”正因如此,省中医院肥胖专科建立了完善的健康管理体系,有专门的医生和护士定期对患者进行随访管理。“我们经常跟患者强调三点:一是保障睡眠,不要熬夜;二是好好吃饭,三餐规律,吃健康食物;三是适量运动。再配合中医药调整,反弹的比例要比单纯打针的人群低得多。”肖明中说。 编辑:李可欣


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